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Science Sparks @ ACTREC
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 4
th August 2025 |
Vol. No. 14 ; Issue No.694 |
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Publications
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1. Biswas M, Sengupta S, Gandhi KA, Gupta SK, Gera PB, Nayak BS, Jagadeb M, Gota V, Sonawane A (2025). Engineered L-asparaginase variants with enhanced therapeutic properties to improve treatment of childhood acute lymphatic leukemia. Cancer Gene Therapy.
2. Chopra S, Manjunath NV, Gupta A, Mittal P, Jain J, Sawant P, Charnalia M, Ghadi Y, Ghosh J, Rath S, Gupta S (2025). Gynaecological reirradiation with image-guided radiotherapy: Dose response relationship for local control and adverse events in pre-immunotherapy era. Radiotherapy and Oncology
3. Budrukkar A, Kashid SR, Swain M, Ghosh Laskar S, Mittal N, Mahimkar M, Sasidharan A, Patil A, Patel U, Murthy V, Gupta T, Patil V, Joshi A, Noronha V, Sinha S, Kumar A, Menon N, Bal M, Prabhash K, Agarwal JP. Long-term outcomes of consecutive patients of oropharyngeal cancer treated with radical radiotherapy. BJC Report. 3(1):54.
4. Bajaj K, Rath S, Vora D, Parab P, Gulia S, Rane S, Shet T, Ghosh J, Popat P, Bhargava P, Sekar A, Mehta A, Kembhavi Y, Jethwa D, Sarin R, Wadasadawala T, Joshi S, Badwe R, Gupta S (2025) Combination chemotherapy and hormone therapy in patients with hormone receptor positive and HER2 negative metastatic breast cancer. Scientific Reports. 15(1):28172.
5. Giri S, Shah B, Narayan J, Chavan R, Donapati VR, Khare S, Varghese J, Mallick B, Kale A, Sundaram S. Reintervention After Endoscopic Ultrasound-Guided Choledochoduodenostomy for Distal Malignant Biliary Obstruction. Surgical Laparoscopy, Endoscopy & Percutaneous Techniques.35(4):e1382.
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Interesting Reads
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Wijesinghe SKM, Rausch L, Gabriel SS, Galletti G, De Luca M, Qin L, Wen L, Tsui C, Man K, Heyden L, Mason T, Newland LD, Kueh A, Liao Y, Chisanga D, Swatler J, Voulaz E, Marulli G, Errico V, Losurdo A, Rossi GR, Souza-Fonseca-Guimaraes F, Huntington ND, Gebhardt T, Utzschneider DT, Herold MJ, Shi W, Schroeder J, Lugli E, Kallies A (2025) Lymph-node-derived stem-like but not tumor-tissue-resident CD8+ T cells fuel anticancer immunity. Nature Immunology ;26(8):1367-1383.
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Video of the Week
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| Pathogenesis of Urothelial Carcinoma: Insights from Genomic Analysis and Whole-Organ Mapping |
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Upcoming Events
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ONCOSURG 2025
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November 20-22, 2025
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At ACTREC, Tata Memorial Centre, Kharghar
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Do You Know?
In 1997, FDA approved Rituxan (rituximab), the first monoclonal antibody, to treat non-Hodgkin’s lymphoma
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Cancer News
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Beta-HPV can directly cause skin cancer in immunocompromised people.
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NIH, 30/07/2025
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Researchers at the National Institutes of Health (NIH) have shown for the first time that a type of human papillomavirus (HPV) commonly found on the skin can directly cause a form of skin cancer called cutaneous squamous cell carcinoma (cSCC)....
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Inflammation during viral infection can rouse dormant cancer cells.
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Nature, 30/07/2025
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Inflammation can trigger metastasis2, raising the possibility that infections can do the same. Viral infections of the airways are a common occurrence and are associated with lung inflammation. However, whether this inflammation affects dormant cancer cells hadn’t been a focus of research...
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Ovarian tumor immune landscapes offer clues to better therapy.
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MedicalXpress, 31/072025
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To develop and validate their classification system, the researchers analyzed a total of 697 primary and recurrent tumor samples from five independent clinical cohorts. The immune classifier they developed—based on the degree to which tumors were infiltrated with the immune system's...
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2025 Advanced Centre for Treatment, Research and Education in Cancer (ACTREC)
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